RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
LFAR1
RNA ID
RNA Type
lncrna
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; etc.
Target
LNC-LFAR1
Pathway
TGF-BETA SIGNALING PATHWAY; NOTCH SIGNALING PATHWAY
PubMed ID
Title
The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFbeta and Notch pathways
Year
2017
Function
"Demonstrate that a liver-enriched lncrna, lnc-lfar1, promotes liver fibrosis and hsc activation by activating tgfbeta and notch signaling."